Spoiler Alert! Uncle Ben Dies in The Amazing Spider-Man!

You get an actor like Martin Sheen as Uncle Ben in The Amazing Spider-Man, and you automatically know that 1) we're going to hear the "With great power comes great responsibility" speech and B) we'll definitely see him croak.
Some snap-shots taken of Sheen and newbie web-slinger Andrew Garfield on set (as per On Location Vacations) confirm the latter.
Interesting to note Marc Webb & Co. opted to make the same dramatic call as Sam Raimi and his team did ten years ago by having Peter Parker present to see his dear old uncle die.
Not a bad call in the slightest, I remember seeing Spider-Man in theaters and thinking, "Hey that's different from the comics!" but in a good way. To have him being told "Oh yeah, by the way, your uncle just got shot off-screen" may be fine for a comic-book, but that shit doesn't fly for a movie.